J.VOGAN · 記録
goalplanswarmgradeiterate
BIO × AI · RESEARCH ↔ AGENTS · LAB-IN-THE-LOOP

Jacob
Vogan

Singularitas biologica

Bio × AI. Building AI tools for life science research, including agentic systems for bioinformatics, structural biology, biomanufacturing, and automated labs. AI progress will ideally speed up the pace of research so people can live healthier, longer lives.

Shared repos include harnesses for long-running multi-agent work, molecular biology suite tools for researchers, and general-purpose AI agent skills.

Focus 専門BIO × AI
Working on 進行中super powers for biological progress
Stack 技術Claude Code · Codex · Gemini · Grok · Kimi
Links リンクGitHub · Hugging Face · X
Jacob Vogan
J.V. · 2026

Projects作品 · SELECTED REPOS

BioTools · 生命

Motif

A molecular biology workbench for Claude Science. View maps and alignments, make entries and notes, and more — all without leaving Claude Science.

TypeScriptmolecular-biologymcp
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Orchestration · 指揮

A Fable of Codexes

Claude Code skill for orchestrating Codex and Claude worker fleets with campaign state, worktrees, review gates, and resumable plans.

agent-skillorchestrationcodex
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BioSymphony · 交響曲

Small Molecules

Small-molecule design workflows: choose tools, plan synthesis, dock ligands, and check ADMET.

Pythonsmall-moleculesdrug-discovery
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BioSymphony · 交響曲

Structure Factory

AI-agent toolkit for structural biology: design binders, map structures, screen candidates, rank results, and prepare cloud-scale runs.

Pythonstructural-biologybinders
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BioSymphony · 交響曲

GeneCluster

Genome-mining workflows for natural products: search public genomes and transcriptomes, compare candidate clusters, and plan follow-up work.

Pythongenome-miningnatural-products
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BioSymphony · 交響曲

BioProspector

Biosynthetic route exploration for target molecules: find enzyme and gene candidates and turn pathway ideas into follow-up searches and experiments.

Pythonbiosynthesisenzymes
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BioSymphony · 交響曲

CryoCore

Cryo-EM workflows for maps, models, figures, state comparison, and local or cloud compute preparation.

Pythoncryo-emstructural-biology
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BioSymphony · 交響曲

Ferm DoE

Fermentation and biomanufacturing experiment planning: choose design families, check scale context, and prepare run packets.

Pythonfermentationbiosafety
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Orchestration · 指揮

NeoCloud Bridge

Run agent workflows on cloud compute with preflight checks, cost caps, artifact receipts, and cleanup.

Pythoncloud-computeorchestration
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BioTools · 生命

Proteus

Structural biology superpowers for AI coding agents: PyMOL, ChimeraX, AlphaFold DB, RCSB PDB, UniProt, and Rosetta workflows.

Pythonstructural-biology
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BioTools · 生命

BioVoice

Talk to your protein structures. Voice control for PyMOL, ChimeraX, AlphaFold, and Rosetta on the OpenAI Realtime API.

TypeScriptalphafoldmolecular-visualization
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Agent Skills & Local AI · 道具

Valar

Local speech stack for Apple Silicon: TTS, ASR, forced alignment, voices, daemon, and MCP bridge.

Swiftapple-siliconasr
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Orchestration · 指揮

Telegram Codex Bridge

Local-first bridge: OpenAI Codex Desktop ↔ Telegram bot. Text, files, voice notes, and optional realtime calls.

TypeScriptcodexlocal-first
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Agent Skills & Local AI · 道具

Daneel

Skill that scaffolds a multi-model chatbot for Telegram or Discord. Claude, GPT, Gemini, and OpenAI-compatible backends. Only approved users can reach it, with prompt injection blocked by default.

Pythonai-agentai-safety
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Orchestration · 指揮

Symphony Claude Lane

Portable skill for adding a Claude Code lane to OpenAI Symphony + Linear workflows.

Shellagent-skilllinear
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Orchestration · 指揮

Symphony Linear Starter

Self-improving starter skill / operator toolkit for Codex or Claude Code as orchestrator over Symphony workers + Linear.

Pythonai-agentclaude-code
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Agent Skills & Local AI · 道具

yt-agent

AI Agent Tool for terminal-first YouTube search, download, catalog, and clip tooling on yt-dlp.

Pythonai-agentagent-skill
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Agent Skills & Local AI · 道具

WhisperHUD

System-wide voice-to-text for macOS. Hold a hotkey, speak, text appears at your cursor. OpenAI / Gemini / Apple Speech / local — bring your own keys.

Pythonaccessibilitybyok
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